Clinical Study
Evaluating the safety and efficacy of Retinol Regimen 3 after 4 weeks of use
The Study
The purpose of this study was to determine the safety and efficacy of using a warmed 0.1% cosmetic retinol formulation system over a consecutive 4-week period.
26
participants took part in the study
15
minutes before going to bed every night as a night cream
4
weeks use of the Retinol+ Ramp-Up Regimen (0.1% Retinol and RHR Treatments)
100%
Said their skin felt smoother
92%
Said their skin felt hydrated
88%
Said their skin tone appeared more even
84%
Said their skin feels firm and had a reduced appearance of fine lines and wrinkles
100%
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100%
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Ramp-Up Regimen 3
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Ramp-Up Regimen 3
The Results
Participant perception data revealed that after 4 weeks of using the Retinol Ramp-Up Regimen
Ramp-Up Regimen 3The Results
Participant perception data revealed that after 4 weeks of using the Retinol Ramp-Up Regimen
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Ramp-Up Regimen 3
More even skin tone and reduction of fine lines
Ramp-Up Regimen 3More even skin tone and reduction of fine lines
Images were taken with a VISIA CA camera on day 1 of the study and again on day 29 after completing the 28-day regimen.
Images were taken with a VISIA CA camera on day 1 of the study and again on day 29 after completing the 28-day regimen.
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Ramp-Up Regimen 3
Our Retinol Ramp-Up Regimen minimizes the adverse effects of retinization
Ramp-Up Regimen 3Our Retinol Ramp-Up Regimen minimizes the adverse effects of retinization
A Dermatologist assessed the health of the skin edema, erythema, and dryness at baseline and following 4 weeks use of the Retinol+ Ramp-Up System.
No clinically assessed edema or dryness were reported for any participant at baseline or 4 weeks. A small reduction in erythema (redness) was reported over the course of 4 weeks (p=0.016).
The retinol ramp-up regimens were found to be safe and effective.
A Dermatologist assessed the health of the skin edema, erythema, and dryness at baseline and following 4 weeks use of the Retinol+ Ramp-Up System.
No clinically assessed edema or dryness were reported for any participant at baseline or 4 weeks. A small reduction in erythema (redness) was reported over the course of 4 weeks (p=0.016).
The retinol ramp-up regimens were found to be safe and effective.
Take the guesswork out of retinol
The Retinol+ Collection and Ramp-Up Regimens have been developed to gradually increase the concentration of retinol as your skin’s tolerance builds. This gradual increase process is called retinization.
Each Regimen consists of 28 Opoule™ Treatments that are clearly laid out for 4 weeks of nighttime treatment.These regimens also sequence in a calming and comforting RHR Overnight Mask for the ‘nights off’ with ingredients such as allantoin, hyaluronic acid, peptides to restore the skin barrier, hydrate and renew. You use one Opoule Treatment each night. It’s that simple.
There are three treatment Regimens: Regimen 1 includes a concentration of .025% retinol, Regimen 2 is .05% retinol and Regimen 3 is .1% retinol.
If you’re new to retinol, you can start with Regimen 1. If you’re pre-conditioned, start with Regimen 3!
Ramp-Up Regimen 1
Treat
Retinol+ Treatment
Specificity
R1 Opoule™ Treatment 0.025% Retinol
Restore
RHR Overnight Mask
Skin Types
Dry, Normal, Combo, Sensitive
Skin Conditions
Dull, dehydrated, tired looking, flaky or rough textured
Benefits
Encourages cellular turnover for a fresher, brighter appearance
Ramp-Up Regimen 2
Treat
Retinol+ Treatment
Specificity
R2 Opoule™ Treatment 0.05% Retinol
Restore
RHR Overnight Mask
Skin Types
Dry, Normal, Combo, Sensitive
Skin Conditions
Dull, dehydrated, tired looking, flaky or rough textured
Benefits
Encourages cellular turnover for a fresher, brighter appearance
Ramp-Up Regimen 3
Treat
Retinol+ Treatment
Specificity
R3 Opoule™ Treatment 0.1% Retinol
Restore
RHR Overnight Mask
Skin Types
Dry, Normal, Combo, Sensitive
Skin Conditions
Dull, dehydrated, tired looking, flaky or rough textured
Benefits
Encourages cellular turnover for a fresher, brighter appearance