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Ramp-Up Regimen 3

Retinol Realized.

Advanced potency, easy cadence. Reap the rewards. Our highest concentration Regimen, ideal for skin that is preconditioned with Ramp-Up Regimen 2.  Regimen 3 is comprised of the R3 Opoule Treatment 0.1% Retinol and the RHR Overnight Mask. Includes four week supply of Retinol+ Ramp-Up Regimen 3.

Formulated for use with the OPULUS Activator only. 

Clinically proven to be safe and gentle.

Benefits - icon

Benefits: Encourages cellular turnover for a fresher, brighter appearance

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Skin Types: Dry, Normal, Combination and Sensitive

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Skin Conditions: Dull, dehydrated, tired looking, flaky or rough textured

  • Choose your frequency:


    You can update your subscription at anytime.

  • Select Regimen:

    Ramp-Up Regimen Guide

    Each Regimen is comprised of 14 Retinol+ Treatment and 14 RHR Overnight Mask. It has all you need for 4 complete weeks of nightly rejuvenation with Retinol and more.

    Regimen 1

    0.025% RETINOL

    If you are new to retinol treatments and your skin is ultra-sensitive or reactive, we recommend starting with our lowest retinol concentration of .025%. You will still experience peak potency while your skin acclimates to retinol and remains protected and hydrated.

    Regimen 2

    0.05% RETINOL

    We recommend Regimen 2 as a continuation of Regimen 1 for sensitive skin, which is now ready for higher retinol concentration. Regimen 2 has a retinol concentration of .05%.

    Regimen 3

    0.1% RETINOL

    If you have normal skin, we recommend you start with Regimen 3, our highest and most effective retinol concentration at .1%.

Do you have The Activator?
The Activator
The Activator

It's like having a personal lab.

The OPULUS Activator provides a thermal blending process calibrated to reach the optimal temperature for heat amplified product absorption. When the OPULUS Activator pressure-opens an Opoule™ Treatment, it releases the inner Core of the Opoule containing the suspended key active ingredients, while the heated bowl melts the outer coat. The Trefoil Blade circulates at varied speeds unifying the two layers into one smooth, freshly activated formula to be applied at peak potency.

The OPULUS Activator was designed to be used only with OPULUS Formulations.

30-day Satisfaction Guaranteed
Complimentary shipping & returns
  • Retinol+ Ramp-Up Night Cream Regimen R3

  • 01 Cleanse and dry skin, select your nightly Opoule Treatment.

    02 Remove the Activator lid, place Opoule Treatment into the bowl and replace lid.

    03 Press the Activator button. In 100 seconds your fresh, blended treatment is warm and ready to apply at peak potency.

  • C10-18 Triglycerides, Polymethylsilsesquioxane, Caprylic/Capric Triglyceride, Tribehenin, Distarch Phosphate, Silica, Glyceryl Laurate, Tristearin, Glyceryl Stearate Citrate, Tetrahexyldecyl Ascorbate, Bakuchiol, Ceramide III, Retinol, Hydrogenated Olive Oil, Polyhydroxystearic Acid, Hippophae Rhamnoides (Sea Buckthorn) Fruit Oil, Polyglyceryl-3 Polyricinoleate, Olea Europaea (Olive) Fruit Oil, Tocopherol, Lecithin, Olea Europaea (Olive) Oil Unsaponifiables, Rosmarinus Officinalis (Rosemary) Leaf Extract


Star Ingredients

  • Treat

    Retinol+ Treatment

    Retinol+ Treatment image

    Pure retinol

    The most effective form for cosmetic use to encourage rejuvenation

    Ceramide III

    Protect skins barrier and counter dryness that is often associated with using retinol

    Tetrahexyldecyl Ascorbate

    Lipid soluble Vitamin C, an antioxidant and skin brightening booster

  • Restore

    RHR Overnight Mask

    RHR Overnight Mask image


    Suspended in the Opoule Treatment at an optimized concentration for skin soothing


    Patented peptide sequence derived from epidermal growth factor proteins for skin firming

    Sodium Hyaluronate

    A powerful humectant to bind moisture for supple and deeply hydrated skin

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Clinically proven safe & gentle

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No added preservatives or parabens

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No artificial color or fragrance

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Formulated without phlalates, silicones

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Assembled, formulated and manufactured in the USA

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Cruelty free



The System elevates routine into ritual and changes the game on results. Potent active skincare blended the moment you want it — at the touch of a button, applied warm for optimized absorption. This is the future of skincare — and it’s here, elegantly streamlined and gorgeously effective.


  • The patented Opoule™ Formulations are designed to optimize key actives and minimize preservatives. With the patented thermal blending provided by our Activator, the process is calibrated to the optimal temperature, helping greater benefits sink in. And it feels amazing! The duo delivers skincare at peak potency, and each application is ready in seconds with just one step.

  • The OPULUS Activator was designed to be used only with OPULUS Formulations.

  • No, there are no plastics nor pods to toss. Opoule Treatments are self-contained and made entirely out of skincare ingredients. There is a convenient paper wrap that makes it easy to lift from the carton. This wrap is recyclable.

Additional questions?

Check out our FAQ page or chat with us.