The Retinol+ Starter System

Rated 4.7 out of 5
Based on 12 reviews

Your journey with us start with the activator and a first treatment. 28 Opoule™ Treatments that offer precision, peak potency and personalization. This is all you need for OPULUS™ transformation.

Clinically proven to be effective yet surprisingly gentle.

Choose your plan:
Select your Ramp-Up Regimen: Regimen guide
Regimen 1 0.025% RETINOL
Regimen 2 0.05% RETINOL
Regimen 3 0.1% RETINOL
Not sure what to pick?
  • Satisfaction guarantee
  • Free shipping, always
  • Two year warranty


Retinol Ramp-Up

With Board-certified Dermatologist Dr. Marnie Nussbaum

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Retinol Ramp-Up

With Board-certified Dermatologist Dr. Marnie Nussbaum

Watch Now
The Lab Personalized
How Freshly Activated Beauty Happens

Small. Chic. Powerful. It elevates routine into ritual and changes the game on results. Today it's Retinol, soon your Activator will hit refresh on your whole beauty routine.

The OPULUS Activator lid and base act as a mortar and pestle to pressure-open an Opoule Treatment and release the inner Core, while the heated bowl melts the outer Coat. Through high-shear forces, the Trefoil Blade circulates at varied speeds unifying the two parts into one smooth, freshly activated formula.

The OPULUS Activator bowl is calibrated to gently and rapidly warm each Opoule Treatment to the ideal temperature for optimized absorption and a luxurious feel.

One press of the button for total transformation. Ready in a minute, easy to clean, too.

Retinol+ Ramp-Up™ regimens
reap retinol’s rewards without trade offs

In each Regimen is all you need for 4 complete weeks of nightly Retinol rejuvenation and more, perfectly timed and measured. See results not reactivity.

Three regimens ramp up the retinol concentration over time as skin adapts to its powers.

Recovery from retinol that’s more than rest. RHR overnight mask comes on the right nights to not only soothe and hydrate but firm and rejuvenate with peptides.

Each night just use the one Opoule Treatment. No guesswork on what to use, when to use it or how much.

Guesswork gone. Rediscover Retinol.

Retinol works. It’s still the top ingredient recommended by dermatologists, yet so hard to get right. Too much? Skin gets dry, red or both. Too little? Nothing happens. OPULUS Retinol+ is the first of its kind, designed for skin’s natural adaptation process. This is what Retinol was always made to do.

Helps skin at every age and stage:

Softens wrinkles and lines

Helps even skin tone

Smooths rough texture and pore visibility

Encourages cellular turnover for a fresher, brighter appearance

Starter system
what's inside

Retinol+ Ramp-Up Night Cream Regimen (choose your level: 1, 2 or 3) 

OPULUS Activator Appliance

Wireless Charging Base

USB Cord + Wall Plug

Microfiber Protective Pouch

Luxe Applicator Activator

Cleaning Brush

Retinol+ Opoule Treatments
Retinol Reimagined

Anhydrous (waterless) applications that are freshly activated and transformed into a novel rich serum-to-cream texture. Available in three highly stable progressive Retinol concentrations R1 (.025%) R2 (.05%) R3 (.1%).

Retinol is notoriously unstable in the presence of water. Not with OPULUS, our Retinol+ Opoule Treatments are undiluted with water, based solely on skin protecting and nourishing rich lipids. Without being watered down, the formulation is now high in stability and low in preservatives, giving you a fresher product applied at peak potency.

  • Pure Retinol — the most effective form for cosmetic use to encourage rejuvenation, nestled within the Opoule Core and protected by the Coat for high stability
  • Ceramide III — skin-identical emollient to protect skins barrier and counter dryness that is often associated with using retinol.

  • Tetrahexyldecyl Ascorbate — lipid soluble Vitamin C, an antioxidant and skin brightening booster

C10-18 Triglycerides, Polymethylsilsesquioxane, Caprylic/Capric Triglyceride, Tribehenin, Distarch Phosphate, Silica, Glyceryl Laurate, Tristearin, Glyceryl Stearate Citrate, Tetrahexyldecyl Ascorbate, Bakuchiol, Ceramide III, Retinol, Hydrogenated Olive Oil, Polyhydroxystearic Acid, Hippophae Rhamnoides (Sea Buckthorn) Fruit Oil, Polyglyceryl-3 Polyricinoleate, Olea Europaea (Olive) Fruit Oil, Tocopherol, Lecithin, Olea Europaea (Olive) Oil Unsaponifiables, Rosmarinus Officinalis (Rosemary) Leaf Extract

Phthalates, parabens, mineral oil, artificial color, fragrance, silicones, or cruelty.

RHR Overnight Mask
Restore. Hydrate. Rejuvenate. RHR.

A richly textured no-rinse mask that is as comforting to put on as it is amazing to wake up in. See calm, glowing, cushiony skin that feels firm and looks rejuvenated.

Allantoin is a skin-soothing savior. Prized for both calming and smoothing properties, yet, in cosmetic labs it’s a fussy ingredient. Studies prove that Allantoin is its efficacious best at a 2% concentration in the formulation. That’s not an easy achievement for traditional skin care products, which contain less than half that. Easy enough for us at OPULUS. Thanks to our patent-pending Opoule Formulations that separate key ingredients in two parts, the Coat and Core, our genius new chemistry can get the full 2% in the final blended RHR overnight mask. Get more rest(oration), while you sleep.

  • Allantoin — suspended in the Opoule Treatment at an optimized concentration for skin soothing.

  • Heptapeptide-7 — patented peptide sequence derived from epidermal growth factor proteins (EGF) for skin firming.

  • Sodium Hyaluronate — A powerful humectant to bind moisture for supple and deeply hydrated skin.

C10-18 Triglycerides, Polymethylsilsesquioxane, Glycerin, Propanediol, Water, Cetearyl Alcohol, Microcrystalline Cellulose, Moringa Oil/Hydrogenated Moringa Oil Esters, Lauryl Laurate, Allantoin, Tetrahexyldecyl Ascorbate, Carnosine, Heptapeptide-7, Hydrogenated Starch Hydrolysate, Tocopherol, Aphanizomenon Flos-Aquae Extract, Sodium Hyaluronate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Glyceryl Stearate Citrate, Coco-Glucosides, Lecithin, Citric Acid, Xanthan Gum, Vanillin, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Corallina Officinalis Extract, Coccinia Indica Fruit Extract, Solanum Melongena (Eggplant) Fruit Extract, Aloe Barbadensis Flower Extract, Simmondsia Chinensis (Jojoba) Seed Oil, Ocimum Sanctum Leaf Extract, Ocimum Basilicum (Basil) Flower/Leaf Extract, Curcuma Longa (Turmeric) Root Extract

Phthalates, parabens, mineral oil, artificial color, fragrance, silicones, or cruelty.

How to use

Cleanse and dry skin, select your nightly Opoule Treatment.


Remove the Activator lid, place Opoule Treatment into the bowl and replace lid.


Press the Activator button. In 60 seconds your fresh, blended treatment is warm and ready to apply at peak potency.

“I've found the one-and-done Ramp-Up Nightly Regimen treatment is all I need to keep my skin's appearance and health in top shape. It’s all there in the Opoule Treatment.“
- Candace Moreno @TheLAFacialist

three month ramp-up subscription program
guesswork gone

Consistency is key to transform your skin and optimize results. Replenishment made effortless with our 3-month subscription program. Subscribe to receive the OPULUS Activator and all three Ramp-Up Regimens sent to you automatically. Your skin benefits from the gradual increase in retinol concentration combined with deep hydrators, soothers, and antioxidants at peak potency. When you order the Ramp-Up Subscription Program, you will receive:

First Shipment

Receive the OPULUS™ Activator + Regimen 1 to allow skin to acclimate to retinol gradually and gently, begin reaping its rewards at 0.025%.

Second Shipment

Four weeks later, receive Regimen 2 to rejuvenate and condition skin at 0.05% concentration.

Third Shipment

Final shipment, receive Regimen 3 for ongoing results and optimized retinol concentration at 0.1%.

Your credit card will be automatically charged $165 a month for three months.

30 Day Money Back Guarantee: Every OPULUS order includes a 30-day money-back guarantee of the purchase price less shipping and handling.

Good Timing for Retinol+ Ramp-Up

Dr. Marnie Nussbaum reveals why Retinol is the gold standard after 4 decades.

Read Here